Annotating principal splice isoforms

APPRIS is a system for annotating alternative splice isoforms and selecting principal isoforms for protein-coding genes in human, mouse and selected species.

APPRIS Database

Access annotations for the species annotated in the database via gene symbol or identifier.

Access the web database

APPRIS WebServer

Annotate splice isoforms for vertebrate genes that are not in the APPRIS Database.

Run the web server

APPRIS WebServices

Annotate genes and transcripts automatically and access queries through RESTful web services.

Go to the API interface

Important Isoforms

View data on functionally important alternative splicing events in human.

View key isoform data

APPRIS Downloads

Access APPRIS data files, filtering by species, genome assembly, or dataset.

Access APPRIS data files


Browse through complete APPRIS datasets via our HTTP site.

Browse APPRIS datasets

To find out more about APPRIS, please consult the APPRIS help pages.

If you have any questions or comments, do not hesitate to contact us.